Members > Faculty Members

Adélia Sequeira

Institutional Address

Instituto Superior Técnico (IST)
Av. Rovisco Pais 1
1049-001 LISBOA


Phone: +351 218417073 | Email: adelia.sequeira@math.tecnico.ulisboa.pt | Web: www.math.ist.utl.pt/~asequeir

Position

Full Professor, Instituto Superior Técnico, Universidade de Lisboa

Area

Mathematical Modeling in Biomedicine

Principal Area

Mathematical and computational modelling of the cardiovascular system

Other Area

Numerical analysis of differential equations. Mathematical and numerical modeling in Fluid Mechanics.

Qualifications

  • Habilitation in 'Mathematics', IST-UTL, Lisbon, Portugal, 2001
  • PhD in 'Mathematics - Numerical Analysis', FCUL, Lisbon, Portugal, 1985
  • Doctorat de 3ème Cycle in 'Mathematics - Numerical Analysis', Univ. Paris VI, France, 1981.
  • DEA in 'Mathematics - Numerical Analysis', Univ. Paris VI, France, 1978.
  • Licenciatura in 'Mathematics', FCUL, Lisboa, Portugal, 1973.

 

Editor in International Journals

  • ISRN Mathematical Physics (2011 - )
  • Archive of Mechanical Engineering (2011 -)
  • Recent Patents on Computer Science (CSENG) (2008 -)
  • Revista Intern. de Métodos Numéricos para Cálculo y Diseno en Ingeníeria (RIMNI) (2009 -)
  • Mathematical Modelling of Natural Phenomena (MMNP) (2010, 2013)
  • Conference Papers in Mathematics (2013 -)

Publications

Papers in International Journals

Kafi, Oualid; Tiago, Jorge; Sequeira, Adélia (2017) Numerical Simulations of a 3D Fluid-Structure Interaction Model for Blood Flow in an Atherosclerotic Artery. Mathematical Biosciences and Engineering: 14, 179-193.
Javad Hatami; Tiago, Jorge; Sequeira, Adélia (2016) Computational modeling of megakaryocytic differentiation of umbilical cord blood-derived stem/progenitor cells. Computers and Chemical Engineering: 94, 117-127.
Jantarada, Ana; Gambaruto, A. M.; Tiago, Jorge; Sequeira, Adélia (2016) Computational advances applied to medical image processing: an update. Open Acess Bioinformatics (Dove Medical Press): 8, 1-15.
Silva, Telma; Tiago, Jorge; Sequeira, Adélia (2016) Existence, uniqueness, stability and asymptotic behaviour of solutions for a mathematical model of atherosclerosis. Discrete and Continuous Dynamical Systems - S: 9, 343-362.
Tricerri, Paolo; Dede, L.; Deparis, S. ; Quarteroni, A.; Robertson, A.; Sequeira, Adélia (2015) Fluid-structure interaction simulations of cerebral arteries modeled by isotropic and anisotropic constitutive laws. Computational Mechanics: 55(3), 479-498.
Pavlova, Jevgenija; Fasano, A.; Janela, João; Sequeira, Adélia (2015) Numerical validation of a synthetic cell-based model for blood coagulation. Journal of Theoretical Biology.
Silva, Telma; Sequeira, Adélia; Santos, Rafael F.; Tiago, Jorge (2015) Existence of optimal boundary control for Navier-Stokes with mixed boundary conditions. Portugaliae Mathematica: Volume 72, Issue 2-3, 267–283.
Pavlova, Jevgenija; Janela, João; Sequeira, Adélia (2014) Numerical validation of a synthetic cell-based model of blood coagulation. , (submitted).
Tiago, Jorge; Gambaruto, A. M.; Sequeira, Adélia (2014) Patient-specific blood flow simulations: setting Dirichlet boundary conditions for minimal error with respect to measured data. Mathematical Models of Natural Phenomena: 9(6), 98-116.
Rossi, Simone; Lassila, T.; Ruiz-Baier, R.; Sequeira, Adélia; Quarteroni, A. (2014) Termodinamically consistent orthotropic activation model capturing ventricular systolic wall thickening in cardiac electromechanics. European Journal of Mechanics - A/Solids: 48, 129-142.
Guerra, Telma; Tiago, Jorge; Sequeira, Adélia (2014) Optimal Control in Blood Flow Simulations. International Journal of Non-Linear Mechanics: 64, 57-69.
Silva, Telma; Sequeira, Adélia; Santos, Rafael F.; Tiago, Jorge (2014) Existence, uniqueness, stability and asymptotic behaviour of solutions for a mathematical model of atherosclerosis. , (submitted).
Bras-Rosario, L.; Nunes, C.; Moura, Alexandra; Rocha, I.; Pinto, F.; Sequeira, Adélia (2014) Influence of the baroreflex on the evolution of ventriculo arterial coupling. The Journal of the Federation of American Societies for Experimental Biology: 28(1), 681.3.
Pavlova, Jevgenija; Fasano, Antonio; Sequeira, Adélia (2014) Numerical simulations of a reduced model for blood coagulation. , (submitted).
Sequeira, Adélia; Bodnár, T. (2014) Blood Coagulation Simulations using a Viscoelastic Model. Mathematical Modelling of Natural Phenomena: 9 (06), 34-45.
Guerra, Telma; Tiago, Jorge; Sequeira, Adélia (2014) On the optimal control of a class of non-Newtonian fluids. Annali dell’Universita di Ferrara: 60(1), 133-147.
Fasano, Antonio; Pavlova, Jevgenija; Sequeira, Adélia (2013) A Synthetic Model for Blood Coagulation Including Blood Slip at the Vessel Wall. Clinical Hemorheology and Microcirculation: 54(1), 1-14.
Silva, Telma; Sequeira, Adélia; Santos, Rafael F.; Tiago, Jorge (2013) Mathematical modeling of atherosclerotic plaque formation coupled with a non-Newtonian model of blood flow. Conference Papers in Mathematics: 2013, 405914.
Gambaruto, A. M.; Janela, João; Moura, Alexandra; Sequeira, Adélia (2013) Shear-Thinning Effects of Hemodynamics in Patient-Specific Cerebral Aneurysms. Mathematical Biosciences and Engineering: 10(3), 649-665.
Ramalho, S.; Moura, Alexandra; Gambaruto, A. M.; Sequeira, Adélia (2012) Sensitivity to Outflow Boundary Conditions and Level of Geometry Description for a Cerebral Aneurysm. International Journal for Numerical Methods in Biomedical Engineering: 28(6-7), 697-713.
Moura, Alexandra; Sequeira, Adélia (2012) Modeling and simulation of the human cardiovascular system. CIM Bulletin (International Center for Mathematics): 31, 27-34.
Bodnar, T.; Rajagopal, K. R.; Sequeira, Adélia (2011) Simulation of the Three-Dimensional Flow of Blood Using a Shear-Thinning Viscoelastic Fluid Model. Mathematical Modelling of Natural Phenomena: 6(5), 1-24.
Bodnar, T.; Sequeira, Adélia; Prosi, M. (2011) On the Shear-Thinning and Viscoelastic Effects of Blood Flow Under Various Flow Rates. Applied Mathematics and Computation: 217(11), 5055-5067.
Gambaruto, A. M.; Janela, João; Moura, Alexandra; Sequeira, Adélia (2011) Sensitivity of Hemodynamics in a Patient Specific Cerebral Aneurysm to Vascular Geometry and Blood Rheology. Mathematical Biosciences and Engineering: 8(2), 409-423.
Smith, Keith D.; Sequeira, Adélia (2011) Micro-Macro Simulations of a Shear-Thinning Viscoelastic Kinetic Model: Applications to Blood Flow. Applicable Analysis: 90(1), 227-252.
Sellountos, Euripides; Sequeira, Adélia; Polyzos, Demosthenes (2011) A New LBIE Method for Solving Elastodynamic Problems. Engineering Analysis with Boundary Elements: 35(2), 185-190.
Sequeira, Adélia; Santos, Rafael F.; Bodnar, Tomas (2011) Blood Coagulation Dynamics: Mathematical Modeling and Stability Results. Mathematical Biosciences and Engineering: 8(2), 425-443.
Janela, João; Moura, Alexandra; Sequeira, Adélia (2010) Absorbing Boundary Conditions for a 3D Non-Newtonian Fluid-Structure Interaction Model for Blood Flow in Arteries. International Journal of Engineering Science: 48(11), 1332-1349.
Gambaruto, A. M.; Moura, Alexandra; Sequeira, Adélia (2010) Topological Flow Structures and Stir Mixing for Steady Flow in a Peripheral Bypass Graft with Uncertainty. International Journal for Numerical Methods in Biomedical Engineering: 26(7), 926-953.
Janela, João; Pontrelli, G.; Sequeira, Adélia; Succi, S.; Ubertini, S. (2010) Unstructured Lattice Boltzmann Method for Hemodynamic Flows with Shear-Dependent Viscosity. International Journal of Modern Physics C: 21(6), 795-811.
Sellountos, Euripides; Sequeira, Adélia; Polyzos, D. (2010) Solving Elastic Problems with Local Boundary Integral Equations (LBIE) and Radial Basis Functions (RBF) Cells. CMES: Computer Modeling in Engineering & Sciences: 57(2), 109-135.
Janela, João; Moura, Alexandra; Sequeira, Adélia (2010) A 3D Non-Newtonian Fluid-Structure Interaction Model for Blood Flow in Arteries. Journal of Computational and Applied Mathematics: 234(9), 2783-2791.
Sellountos, Euripides; Sequeira, Adélia; Polyzos, D. (2009) Elastic Transient Analysis with MLPG(LBIE) Method and Local Rbfs. CMES: Computer Modeling in Engineering & Sciences: 41(3), 215-241.
Robertson, A. .; Sequeira, Adélia; Owen, R. (2009) Rheological models for blood. Cardiovascular Mathematics: 1, 211-241 .
Sequeira, Adélia; Artoli, A. M.; Silva-Herdade, A. S.; Saldanha, Maria Carlota (2009) Leukocytes Dynamics in Microcirculation Under Shear-Thinning Blood Flow. Computers & Mathematics with Applications: 58(5), 1035-1044.
Borges, L.; Sequeira, Adélia (2008) Numerical simulation of a viscoelastic fluid with a preconditioned Schwarz method. Banach Center Publ., Inst. Math, Polish Acad. Sc.: 81, 65-80.
Bodnar, T.; Sequeira, Adélia (2008) Numerical Simulation of the Coagulation Dynamics of Blood. Computational and Mathematical Methods in Medicine: 9(2), 83-104.
Carapau, F.; Sequeira, Adélia (2008) 1D dynamics of a second-grade viscous fluid in a constricted tube. Banach Center Publ., Inst. Math, Polish Acad. Sc.: 81, 95-103.
Artoli, A. M.; Sequeira, Adélia; Silva-Herdade, A. S.; Saldanha, C. (2008) Localized Hydrodynamics of Clustering Leukocytes. Clinical Hemorheology and Microcirculation: 39(1-4), 375-380.
Janela, João; Sequeira, Adélia (2008) On a constrained minimization problem arising in hemodynamics. Banach Center Publ., Inst. Math, Polish Acad. Sc.: 81, 227-241.
Nazarov, Serguei A.; Sequeira, Adélia; Specovius-Neugebauer, Maria; Videman, J. H. (2008) Artificial Boundary Conditions for Viscoelastic Flows. Mathematical Methods in the Applied Sciences: 31(8), 937-958.
Sellountos, Euripides; Sequeira, Adélia (2008) A Hybrid Multi-Region BEM/LBIE-RBF Velocity-Vorticity Scheme for the Two-Dimensional Navier-Stokes Equations. CMES-Computer Modeling in Engineering & Sciences: 23(2), 127-147.
Sellountos, Euripides; Sequeira, Adélia (2008) An Advanced Meshless LBIE/RBF Method for Solving Two-Dimensional Incompressible Fluid Flows. Computational Mechanics: 41(5), 617-631.
Artoli, A. M.; Sequeira, Adélia; Silva-Herdade, A. S.; Saldanha, C. (2007) Leukocytes Rolling and Recruitment by Endothelial Cells: Hemorheological Experiments and Numerical Simulations. Journal of Biomechanics: 40(15), 3493-3502.
Silva-Herdade, Ana Santos; Artoli, A. M.; Sequeira, Adélia; Saldanha, C. (2007) Leukocyte Rolling and Recruitment by Endothelial Cells: Hemorheological Experiments and Numerical Simulations. Inflammation Research: 56, S388-S389.
Robertson, AM; Sequeira, Adélia (2005) A Director Theory Approach for Modeling Blood Flow in the Arterial System: An Alternative to Classical 1D Models. Mathematical Models & Methods in Applied Sciences: 15(6), 871-906.

Papers or Chapters in Edited Books

Bodnár, Tomáš; Fasano, Antonio; Sequeira, Adélia (2014) Mathematical models for blood coagulation. Fluid-Structure Interaction and Biomedical Applications. Advances in Mathematical Fluid Mechanics, Springer Basel, 483-569.
Ramalho, S.; Moura, Alexandra; Gambaruto, A. M.; Sequeira, Adélia (2013) Influence of blood rheology and outflow boundary conditions in numerical simulations of cerebral aneurysms. Mathematical Methods and Models in Biomedicine, Lecture Notes on Mathematical Modelling in the Life Sciences, Springer, New York, 149-175.
Fasano, A.; Santos, Rafael F.; Sequeira, Adélia (2012) Blood coagulation: a puzzle for biologists, a maze for mathematicians. Modeling of Physiological Flows, MS&A — Modeling, Simulation and Applications, Springer Milan : 5, 41-75.
Ramalho, S.; Moura, Alexandra; Gambaruto, A. M.; Sequeira, Adélia (2012) Importance of the choice of mathematical model and level of geometry description in computational hemodynamics of cerebral aneurysms. Mathematical Models and Methods in Biomedicine, American Institute of Mathematical Sciences, 151-178.
Pires, Marília; Sequeira, Adélia (2011) Flows of generalized Oldroyd-B fluids in curved pipes. Parabolic Problems, Progress in Nonlinear Differential Equations and Their Applications, Springer Basel: 80, 21-43.
Sequeira, Adélia; Moura, Alexandra; Janela, João (2010) Towards a geometrical multiscale approach to non-Newtonian blood flow simulations. Advances in Mathematical Fluid Mechanics, Springer Berlin Heidelberg, 295-309.
Bodnár, T. ; Sequeira, Adélia (2010) Numerical study of the significance of the non- Newtonian nature of blood in steady flow through a stenosed vessel. Advances in Mathematical Fluid Mechanics, Springer Berlin Heidelberg, 83-104.
Robertson, A. M.; Sequeira, Adélia; Kameneva, M. (2008) Hemorheology. In G.P. Galdi, R. Rannacher, A.M. Robertson, and S. Turek, eds., Hemodynamical Flows: Modeling, Analysis and Simulation, Series: Oberwolfach Seminars, Birkhauser: 37, 63-120.
Artoli, Abdel Monim; Sequeira, Adélia (2006) Mesoscopic Simulations of Unsteady Shear-Thinning Flows. Computational Science - Iccs 2006, PT 2, Proceedings (Ed. Alexandrov, VN et Al.). Lecture Notes in Computer Science: 3992, 78-85.

Communications in Conference Proceedings

Santos, Rafael F.; Sequeira, Adélia (2014) Time scaling on a reduced blood coagulation model. Proceedings of the 14th International Conference Computational and Mathematical Methods in Science and Engineering (CMMSE 2014), July 3-7, Rota, Cadiz – Spain.
Janela, João; Pavlova, Jevgenija; Fasano, A. ; Sequeira, Adélia (2014) A Synthetic cell-based model for blood clotting modelling. Proceedings of the 14th International Conference Computational and Mathematical Methods in Science and Engineering (CMMSE 2014), July 3-7, Rota, Cadiz – Spain.
Sequeira, Adélia (2014) Coupling multiscale fluid-structure interaction models for blood flow simulations. Proceedings of the 10-th Conference on Dynamical Systems, Differential Equations and Applications (AIMS), Madrid, Spain, July 7-11.
Pavlova, Jevgenija; Fasano, A.; Janela, João; Sequeira, Adélia (2014) A model approach to understand blood-clotting dynamics. Proceedings of the 11th World Congress on Computational Mechanics (WCCM XI), 5th European Conference on Computational Mechanics (ECCM V), 6th European Conference on Computational Fluid Dynamics (ECFD VI), July 20-25, Barcelona, Spain.
João, A.J.; Gambaruto, A. M.; Sequeira, Adélia (2014) Impact of robust image processing to reduce error in computational hemodynamics. Proceedings of the 11th World Congress on Computational Mechanics (WCCM XI), 5thEuropean Conference on Computational Mechanics (ECCM V), 6th European Conference on Computational Fluid Dynamics (ECFD VI), July 20 - 25, Barcelona, Spain.
Guerra, Telma; Tiago, Jorge; Sequeira, Adélia (2013) Towards a data assimilation method for blood circulation. Proceedings of the 13th International Conference of Computational and Mathematical Methods in Science and Engineering (CMMSE), Almeria.
Jantarada, Ana; Gambaruto, A. M.; Sequeira, Adélia (2012) The Effects of Medical Image Processing Techniques on the Computational Haemodynamics. The IEEE 2nd Portuguese Meeting in Bioengineering, 1-4.
Gambaruto, A. M.; Sequeira, Adélia (2010) Study of Geometrical Uncertainty Stemming From Different Reconstruction Procedures on the Flow Field for a Peripheral Bypass Graft.. Proceedings of IEEE 2010 Annual International Conference, Engineering in Medicine and Biology Society (EMBC), 4076-4079.
Pavlova, Jevgenija; Sellountos, Euripides; Sequeira, Adélia (2010) Meshless LBIE–RBF Velocity – Vorticity Formulation for 2D Fluid Flows. Proceedings of ECOMAS, CFD 2010.

Edition of Books

Sequeira, Adélia; Volpert, V.  (2014) Modeling of Natural Phenomena. Blood Flows, Cambridge: 9(6), ISSN: 0973-5348.
Sequeira, Adélia; Rannacher, R. (2010) Advances in Mathematical Fluid Mechanics (Dedicated to G.P. Galdi on his 60th birthday). Springer Verlag.
Baker, Christopher T. H.; Ford, Neville J.; Diogo, Teresa; Lima, Pedro M.; Sequeira, Adélia (2010) Special issue: Third International Workshop on Analysis and Numerical Approximation of Singular Problems. Journal of Computational and Applied Mathematics: 234(9), 2617.
Pereira, J.C.F.; Sequeira, Adélia; Pereira, J.M.C.; Janela, João; Borges, L. (2010) Book of Abstracts. The 5th European Conference on Computational Fluid Dynamics, 14-17 June, 2010, Lisbon, Portugal: Vol. I, Vol. II .

Papers in National Scientific Journals

Moura, Alexandra; Sequeira, Adélia (2011) A Matemática do Sistema Cardiovascular. Gazeta de Matemática: 164.
Sequeira, Adélia (2010) Hemorheology and Mathematical Models. Boletim da Sociedade Portuguesa de Hemorreologia e Microcirculação: 25(3), 5-17.

Other Information

Honors and Awards

  • Medal of Merit of the Faculty of Mechanical Engineering, Czech Technical University in Prague, 2011.
  • First Prize in the area of Pure and Applied Mathematics - UTL/Santander Totta Scientific Awards 2010.
  • Honorable Mention in the area of Pure and Applied Mathematics - UTL/Santander Totta Scientific Awards 2008 and 2009.
  • Project SIMCARD (Cardiovascular Imaging, Modeling and Simulation) - International Partnership UTAustin|Portugal endorsed by the industrial EUREKA network (EUREKA 4990)

  Supervising Experience 

  • Post-doc: 13 (since 2001); 3 (presently)
  • PhD: 13 (concluded); 4 (in progress
  • MSc: 9 (concluded); 2 (in progress)

  Leadership of R&D Projects

PI of several national research projects sponsored by INIC, JNICT, POCTI-FCT, International bilateral projects sponsored by CRUP- DAAD and GRICES (with France, Italy, Tunisia, Morocco). PI of an FCT CoLab UTAustin|Portugal Project and of the Portuguese group in 3 European research networks.

  On-going Projects:

  • Mathematical and Computational Modeling in Human Physiology -PHYSIOMATH - Project FCT EXCL/MAT-NAN/0114/2012. Research Centers: CEMAT/IST, IMM/FM/UL, AIDFM/FM/UL,CHUC, IBILI/FM/UC [2013-2016].
  • MRI-Based Computational Modeling of Blood Flow and Nanomedicine Deposition in Patients with Peripheral Arterial Disease: Insights into Disease Management - Project CoLab UT Austin|Portugal (with Thomas J.R. Hughes - PI at UT Austin) [2014-2016].

Seminars

Aplicações da Matemática a Simulações do Sistema Cardiovascular  (2016-11-11) Sala 3.10
Innovative Modeling Techniques for Predictive Medicine (Workshop) (2015-11-12)

Conferences

Workshop on PDE's and Biomedical Applications Lisbon, Portugal  (Organizing Committee, Scientific Committee)
Nonlinear Mechanics and Applications in Life Sciences  IST, Lisbon  (Organizing Committee)